Projects & Partners
Influence of the skeleton remodeling status on tumor cell dissemination and growth of metastases
Universität Hamburg
Michael Amling, Thorsten Schinke
Functional characterization of bone metastases-initiating and radiation resistant cells in prostate cancer
Deutsches Krebsforschungszentrum Heidelberg
Michael Baumann
Technische Universität Dresden
Anna Dubrovska, Mechthild Krause
Nationale Zentrum für Tumorerkrankungen (NCT) Dresden
Claudia Peitzsch
The role of adipocytes in the tumor microenvironment of bone
Universitätsklinikum Erlangen
Tobias Bäuerle, Aline Bozec
Analysis of the role of TAM receptors in myeloma-induced osteoclast activation and their immuno modulatory functions
Universität Hamburg
Isabel Ben Batalla, Sonja Loges
Interaction of junctional adhesion molecules in the myeloma-bone marrow-niche
Universität Würzburg
Andreas Brandl
Characterization of the influence of osteotropic tumors on the osteocyte network and the osteocyte-transmitted regulation of bone turnover
Technische Universität Dresden
Martina Rauner
Universität Hamburg
Björn Busse
Charité-Universitätsmedizin Berlin
Kay Raum
Invasion, colonization and transformation of the bone microenvironment by breast cancer – descriptive and functional examination of membrane leakage and intercellular communication: From cell biology to clinical translation
Technische Universität Dresden
Pauline Wimberger, Denis Corbeil
Influence of myostatin on bone metastasis formation in breast cancer and multiple myeloma
Universität Münster
Berno Dankbar
Examination of the pleiotropic effects of Dickkopf-1 in osteotropic metastasis formation (“homing”) and the colonization of breast cancer cells in bone
Technische Universität Dresden
Tilman Rachner, Andy Göbel
Molecular and functional characterization of bone metastases-building cells in prostate cancer
Universität Regensburg
Miodrag Guzvic, Christoph Klein
Role of Tgif1 f in breast cancer-induced pathological bone remodeling
Universität Hamburg
Eric Hesse, Hanna Taipaleenmäki
The Wnt5a signal pathway in the bone microenvironment of prostate cancer
Technische Universität Dresden
Lorenz Hofbauer, Christine Hofbauer
Molecular and functional characterization of the interface between normal and malign plasma cells and bone cells – from individual-cell-analysis of the reciprocal interaction to their clinical implications in bone disease and survival in multiple myeloma
Universität Heidelberg
Dirk Hose
Universität Würzburg
Franz Jakob
Control of tumor cell-bone metastasis formation through regulation of the F-actin dynamic
Technische Universität Dresden
Rolf Jessberger
Role of tumor-associated macrophages in the bone metastasis formation of zebrafish
Technische Universität Dresden
Franziska Knopf
Regulation of tumor cell dormancy in the development of bone metastasis in humane prostate cancer
Universität Hamburg
Tobias Lange
Functional analysis of the metastatic potential of human breast cancer through the influences of matricellular protein SPARC originating from stromal cells in the bone marrow niche
Universität Frankfurt
Hind Medyouf, Lisa Sevenich
Stromal cells of the bone marrow influence immigration of tumor cells into the bone marrow and tumor growth
Universität Heidelberg
Inaam Nakchbandi
RAI2 as a new inhibitor of the dissemination of cancer cells in the bone marrow
Universität Hamburg
Klaus Pantel, Harriet Wikman-Kocher
Role of TRIM proteins in the colonization of bone and the modulation of the bone microenvironment in metastasized prostate cancer
Universität zu Lübeck
Sven Perner
Role of hypoxie signal pathway proteins in the formation of bone metastases
Technische Universität Dresden
Martina Rauner, Ben Wielockx
Development and validation of a gene expression assay as prognostic and predictive biomarker in prostate cancer bone metastases
Universität Lübeck
Verena-Wilbeth Sailer
Central administration, scientific exchange and clinical translation
Technische Universität Dresden
Lorenz Hofbauer
